Praimera Biotech AG

Developing the next generation of therapeutic antibodies 
– Taught by nature, delivered by artificial intelligence

Technology

Therapeutic area:

Importance and history of antibodies

Monoclonal antibodies (mAbs) have revolutionized the treatment of many debilitating and life threatening diseases including cancer and autoimmune disorders. Their capacity to precisely target specific antigens while minimizing off-target binding has made them a cornerstone in targeted therapy.

With a compound annual growth rate (CAGR) of over 11% from 2024 to 2033, the market size of monoclonal antibodies is expected to grow from about USD 238 billion in 2023 to around USD 680 billion by 2033. (Vision research reports). This highlights the immense medical and market potential of therapeutic antibodies.

Innovative approaches have been instrumental in the success and advance of mAb therapies, increasing safety, efficacy and accessibility. Innovations of the past decades include humanized and fully-human antibodies, antibody-drug conjugates (ADCs) and bispecific antibodies. The beginning of the antibody industry has been characterized by successful platform companies. Now, while these approaches have matured, there is a need for novel antibody engineering platforms with disruptive technologies to create products with improved efficacy and novel properties.

Platform for next generation antibodies

with new functions

We learn from the immense potential of natural antibodies to develop the next generation of biotherapeutics with fundamentally new therapeutic properties, overcoming the existing limitations of targeted immunotherapy. Our approach combines machine learning, computer simulations and cutting-edge wet lab technology to develop novel biotherapeutics.

Proprietary library for next generation antibodies

By creating molecules with specific properties we are disrupting current standards and pushing the boundaries of what is possible today to the next level.

Praimera Biotech AG leverages the enormous potential of AI-driven drug design to establish a library of new therapeutic antibodies with tailored therapeutic properties.  

It is our aspiration to create breakthrough molecules which significantly improve treatment efficacy and potential.

About us

History

The founders of Praimera Biotech AG combine scientific excellence, a record of successful biopharmaceutical drug development and entrepreneurial expertise. The team has a history of jointly developing highly successful biopharmaceutical drugs in various projects, several of which are now on the market. Together, the founders have decades of experience in the field of antibody engineering, the production and characterization of therapeutic proteins, and regulatory approval as well as extensive knowledge of the biopharmaceutical market and the development of start-up companies.

Executive
Board

Dr. Nicolas Combé (CEO/CFO)

Nicolas is heading the administrative and business functions at Praimera. He is one of the founders of the company and has more than 15 years of experience in the biotechnology industry. Prior to starting Praimera, he co-founded and served as CFO as well as member of the Management Board of Formycon AG, a company which is listed on the German Stock Exchange. In his role as CFO, the business graduate was responsible for the company’s successful capital market positioning and various successful financial and strategic transactions.

Dr. Maximilian Biebl (CSO)

Maximilian oversees and leads the scientific activities at Praimera Biotech AG.  He joined Praimera from MorphoSys AG, where he led several analytical groups focused on the characterization of therapeutic antibodies throughout the entire drug life cycle from pre-clinical to commercial stage. He holds a doctoral degree from the Technical University of Munich and brings extensive experience in the field of immunology and the development of therapeutic antibodies.

Supervisory
Board

Super-
visory
Board

Dr. Olaf Stiller (Chairman)

Olaf is a serial entrepreneur and has been involved in a number of successful company formations. He served as CEO of NanoRepro AG and Paedi Protect AG for many years, both of which he also co-founded. At present, he is CEO of Deutsche Kosmetikwerke AG, a company he also helped to set up. 
Further companies he was involved in founding are Formycon AG, alphazoo AG, Deutsche Reinigungswerke AG and Praimera Biotech AG. He currently holds four supervisory board mandates.

Prof. Dr. Johannes Buchner (Vice Chairman)

Johannes has worked on basic aspects of antibody structure and biology throughout his career. He holds the chair of biotechnology at the Technical University of Munich. He is also a founder of Praimera Biotech AG. For his discoveries in the context of protein folding in vivo and in vitro he obtained several awards such as the Warburg Medal and the Neurath award. He is a member of the Bavarian and German Academies of Science.

Prof. Dr. Hristo Svilenov

Hristo belongs to the founders of Praimera and joined the supervisory board in 2024. He is a Professor of Biopharmaceutical Technology at the Technical University of Munich. His research focuses on the development and production of novel biotherapeutics. Hristo obtained his doctoral degree at the Ludwig-Maximilian University of Munich. He has received several prestigious awards and distinctions, including an ERC grant.

Hermann Vogt

Hermann has many years of professional experience in investment banking. Among other things, he was jointly responsible for the bond trading activities of Deutsche Bank AG. Since 2008, he has contributed his expertise in various functions in asset management and as member of supervisory boards in biotech and other industries.

Advisory
Board

Dr. Carsten Brockmeyer

Carsten is a seasoned biopharma manager with a strong background in human biology, biopharmacy and immunology. During his more than 30 years in the biopharma industry, he was Scientific Director at Baxter Immunotherapy, GM at Hexal Biotech, and CEO at Formycon AG. He brought several biopharmaceutical products from idea to EU / US launch and won several prestigious awards for his contributions to the biopharmaceutical industry. Carsten is one of the founders of Praimera Biotech AG.

Prof. Dr. Falk Nimmerjahn

Falk is a global leader in understanding therapeutic antibody activity. His research on understanding the pro- and anti-inflammatory activities of antibodies has transformed the way we think about antibodies and has paved the way for next generation therapeutics. In addition to academic research, he serves as a scientific advisor for many biotech companies which has helped to introduce new therapeutic antibodies for treating cancer and autoimmunity.

Team

Dr. Franziska Hartung

Senior Scientist Immunology

Ramona Absmeier

Senior Scientist Analytics

Tuan Nguyen

Senior Scientist Analytics

Dr. Maria Reif

Director Computational Biology

Dr. Till Siebenmorgen

Associate Director Computational Biology

Richard Zschau

Senior Scientist Computational Biology

Dominik Bartel, M.Sc.

Senior Research Associate Analytics

Laura Meier

Research Associate Analytics

Sarah Prakesch, M.Sc.

Research Associate Cell Culture and Protein Production

Contact

Interested in our work? Please feel free to contact us via info@praimera.com and we will get in touch with you as soon as possible.